Eldepryl

Parkinson's disease is a neurological disorder that affects movement. It is characterized by a shortage of a chemical called dopamine in the brain. Selegiline works by inhibiting the enzyme monoamine oxidase-B, which is responsible for breaking down dopamine in the brain. By inhibiting this enzyme, Eldepryl helps increase dopamine levels, which can improve the symptoms of Parkinson's disease.

Medicine is often used as an adjunct therapy to levodopa, another medication commonly prescribed for Parkinson's disease. By enhancing the effects of levodopa and prolonging its duration of action, Eldepryl can help reduce fluctuations in motor function and improve overall symptom control.

While Eldepryl is primarily used for Parkinson's disease, it may also have other off-label uses, such as in the treatment of depression or cognitive disorders.

How to use

Here are some general guidelines on how to use Eldepryl:

1. Take it with or without food: Medicine can be taken with or without food. However, taking it with food may help reduce stomach upset.
2. Swallow the tablet whole: Take capsules orally with a glass of water. Do not crush, chew, or break the capsules.
3. Follow dietary restrictions: While taking Eldepryl, it is important to follow certain dietary restrictions to avoid potential interactions. Avoid consuming foods that are high in tyramine, such as aged cheeses, cured meats, fermented or pickled foods, and certain alcoholic beverages. Tyramine can interact with Selegiline and may lead to a sudden increase in blood pressure, potentially causing a hypertensive crisis.
4. Be patient: It may take several weeks before you notice the full therapeutic effects of Eldepryl. Continue taking the medication as prescribed, even if you do not experience immediate improvements.

Dosage

The dosage of Eldepryl can vary depending on the condition being treated and individual patient factors. The following are general dosage guidelines:

Parkinson's disease:

• Monotherapy: The usual starting dose for adults is 5 mg taken orally once or twice a day. The dose may be increased gradually, usually at two-week intervals, based on your response and tolerability. The maximum recommended daily dose is 10 mg.
• Adjunct to levodopa: The usual starting dose for adults is 5 mg taken orally twice a day. The dose may be increased gradually, usually at two-week intervals, based on your response and tolerability. The maxium recommended daily dose is 10 mg.

Depressive disorders (off-label use):

• The usual starting dose for adults is 5 mg taken orally once or twice a day. The dose may be increased gradually, based on your response and tolerability. The maximum recommended daily dose is 10 mg.

Side effects

Eldepryl may cause certain side effects. It's important to note that not everyone experiences these side effects, and their severity can vary from person to person. Common side effects may include:

1. Nausea: Eldepryl can cause feelings of nausea or an upset stomach. Taking the medication with food may help reduce this side effect.
2. Insomnia: Some individuals may experience difficulty sleeping or changes in sleep patterns while taking Eldepryl. It is advisable to take the medication in the morning to minimize the risk of insomnia.
3. Dry mouth: Drug can lead to a decrease in saliva production, resulting in a dry mouth. Chewing sugar-free gum, sipping water, or using artificial saliva products can help alleviate this side effect.
4. Dizziness or lightheadedness: Selegiline may cause dizziness or lightheadedness, especially when standing up quickly from a seated or lying position. Taking precautions to stand up slowly and avoid sudden movements can help minimize this side effect.
5. Headache: Some individuals may experience headaches while taking Eldepryl.
6. Gastrointestinal disturbances: Medicine may cause gastrointestinal disturbances such as diarrhea, abdominal pain, or constipation.
7. Increased blood pressure: Eldepryl can occasionally cause an increase in blood pressure. Regular monitoring of blood pressure is important, especially in individuals with a history of hypertension.

Storage

Eldepryl should be stored properly to maintain its effectiveness and ensure its safety. Here are some guidelines for storing:

1. Store at room temperature: Keep drug at a temperature between 68°F (20°C) and 77°F (25°C). Avoid exposing it to extreme temperatures, such as freezing or excessive heat.
2. Protect from light and moisture: Store capsules in its original container, and keep it tightly closed. Protect it from light and moisture, and avoid storing it in areas such as bathrooms or near sinks, where humidity levels may be high.
3. Keep out of reach of children and pets: Store Eldepryl in a secure location that is out of the reach of children and pets.
4. Proper disposal: If you have any unused or expired Eldepryl, it is important to dispose of it properly. Do not dispose of medications in household waste or flush them down the toilet unless specifically instructed to do so. Consult your pharmacist or local authorities for proper disposal methods.
5. Check expiration date: Always check the expiration date on the packaging before using Eldepryl. Do not use the medication if it has expired. Expired medications may not be as effective or could potentially be harmful.

Overdose

An overdose of Selegiline can be serious and potentially life-threatening. If you suspect an overdose or if someone has taken more than the prescribed amount of Eldepryl, it is important to take immediate action. Here's what you should do:

1. Call emergency services: Contact your local emergency number immediately or go to the nearest emergency room. Inform them about the suspected Eldepryl overdose and provide them with all relevant information.
2. Do not induce vomiting: Do not try to induce vomiting unless instructed to do so by medical professionals. Vomiting may not be effective or safe in this situation.
3. Monitor vital signs: Keep an eye on the person's vital signs, including their breathing, heart rate, and blood pressure. If they become unconscious, have difficulty breathing, or experience severe symptoms, seek immediate medical assistance.
4. Provide information: If possible, provide medical professionals with information about the quantity of Eldepryl taken, the time it was taken, and any other pertinent details. This information will assist them in determining the best course of action.
5. Seek medical attention: Once at the hospital or under the care of medical professionals, they will assess the situation and initiate appropriate treatment. Treatment may involve procedures to remove the medication from the body, supportive care to stabilize vital signs, and administration of medications or antidotes as necessary.

Missed Doses

If you miss a dose of Eldepryl, follow these general guidelines:

1. Take the missed dose as soon as you remember: If you realize that you have missed a dose of Eldepryl, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.
2. Do not take extra doses: Do not take an extra dose of Eldepryl to compensate for the missed one. Taking more than the prescribed amount can increase the risk of side effects and may not provide additional benefit.
3. Resume regular dosing schedule: After a missed dose, resume taking Selegiline according to your regular dosing schedule. It is important to maintain the prescribed interval between doses for optimal effectiveness.