Exelon

The exact way Exelon works is not fully understood, but it is believed to increase the levels of certain chemicals in the brain involved in memory, thinking, and overall cognitive function. By doing so, Rivastigmine may help improve cognition, memory, and daily functioning in individuals with dementia.

It is important to note that Exelon does not cure Alzheimer's disease or Parkinson's disease, but it may help manage the symptoms and slow down the progression of the disease in some individuals. The medication is available in oral capsule, oral solution, and transdermal patch forms.

How to use

Medicine is available in different formulations, including oral capsules, oral solution, and transdermal patches. Here are general guidelines for each form:

Oral capsules:

• Take Exelon capsules by mouth with a full glass of water.
• It is usually recommended to take the capsules twice a day, with the morning and evening meals.
• Follow the dosage instructions. Do not exceed the prescribed dose.
• Swallow the capsules whole. Do not crush, chew, or open them.

Oral solution:

• Measure the prescribed dose of Exelon oral solution using the provided oral syringe or dosing spoon.
• Take it by mouth, either directly from the syringe or mixed with a small glass of water, juice, or soft food (e.g., applesauce).
• Take Exelon oral solution twice a day, with the morning and evening meals.

Transdermal patches:

• Apply the Exelon transdermal patch to clean, dry, and intact skin on the upper or lower back, upper arm, or chest.
• Avoid areas with skin irritation, cuts, or wounds.
• Use a different application site each time to minimize skin irritation.
• Follow the instructions provided with the patch regarding application, removal, and disposal.
• The patch is usually applied once daily and should be worn for the prescribed duration, typically 24 hours.
• Replace the patch with a new one at the same time each day.

Dosage

The dosage of Exelon can vary depending on the individual's condition, response to treatment, and the specific formulation prescribed. The following are general dosage guidelines:

Oral capsules:

• The recommended starting dose is usually 1.5 mg twice daily (total daily dose of 3 mg).
• The dosage may be increased gradually based on the individual's response and tolerance, usually at 2-week intervals.
• The target maintenance dose is typically 3-6 mg twice daily (total daily dose of 6-12 mg).
• The maximum recommended dose is 6 mg twice daily (total daily dose of 12 mg).

Oral solution:

• The recommended starting dose is usually 1.5 mg twice daily (total daily dose of 3 mg), using the provided oral syringe or dosing spoon.
• The dosage may be increased gradually based on the individual's response and tolerance, usually at 2-week intervals.
• The target maintenance dose is typically 3-6 mg twice daily (total daily dose of 6-12 mg).
• The maximum recommended dose is 6 mg twice daily (total daily dose of 12 mg).

Transdermal patches:

• The recommended starting dose is usually one 4.6 mg/24 hours patch applied once daily.
• The dosage may be increased gradually based on the individual's response and tolerance, usually at 4-week intervals.
• The target maintenance dose is typically one 9.5 mg/24 hours patch applied once daily.
• The maximum recommended dose is one 13.3 mg/24 hours patch applied once daily.

Side effects

Exelon may cause certain side effects. While not everyone experiences these side effects, it is important to be aware of them. Common side effects can include:

Gastrointestinal symptoms:

• Nausea
• Vomiting
• Diarrhea
• Loss of appetite
• Abdominal pain or discomfort

Central nervous system effects:

• Headache
• Dizziness
• Insomnia (difficulty sleeping)
• Fatigue
• Anxiety

Skin reactions (with transdermal patches):

• Redness or itching at the application site
• Rash or skin irritation

Other possible side effects:

• Muscle weakness
• Tremor (uncontrolled shaking)
• Urinary incontinence (involuntary loss of urine)
• Weight loss

In some cases, Exelon may cause more serious side effects, such as severe gastrointestinal reactions, fainting, or allergic reactions. If you experience any unusual or severe symptoms, seek immediate medical attention.

Storage

To ensure the proper storage of Exelon and maintain its effectiveness, it is important to follow these storage guidelines:

1. Keep medicine in its original container: Store the medication in the original container provided by the manufacturer. The container is designed to protect the medication from light, moisture, and other external factors.
2. Store at room temperature: Keep Exelon at room temperature, typically between 20-25°C (68-77°F). Avoid exposing it to extreme temperatures or direct sunlight.
3. Protect from moisture: Store capsules in a dry place, away from sources of moisture such as bathrooms or kitchen sinks. Avoid storing it near water or in areas with high humidity.
4. Keep out of reach of children: Store Exelon in a secure place out of the reach of children and pets. The medication should only be taken by the individual for whom it was prescribed.
5. Do not transfer between containers: Do not transfer capsules to a different container. The original container is designed to maintain the integrity and stability of the medication.
6. Check expiration date: Ensure that you check the expiration date on the medication packaging. Do not use Rivastigmine past its expiration date, as it may not be effective.

Proper storage helps maintain the quality and potency of Exelon.

Overdose

An overdose of Exelon can be dangerous and should be taken seriously. If you suspect an overdose or have accidentally taken more than the prescribed dose, it is important to seek immediate medical attention or contact your local poison control center.

Symptoms of an Exelon overdose may include:

Severe gastrointestinal symptoms:

• Nausea
• Vomiting
• Diarrhea
• Stomach cramps
• Loss of appetite

Central nervous system effects:

• Severe headache
• Dizziness
• Confusion
• Agitation
• Tremors
• Seizures

Other potential symptoms:

• Slow or irregular heart rate
• Low blood pressure
• Difficulty breathing
• Fainting
• Excessive sweating

Missed Doses

If you miss a dose of Exelon, it is important to take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

Consistency in taking Rivastigmine is important for its effectiveness in managing the condition it is prescribed for. It is recommended to establish a routine to help you remember to take your medication at the same time each day. Setting reminders, using pill organizers, or incorporating it into your daily routine can be helpful strategies.

 Exelon (pdf)