Frumil

Here is some information about Frumil:

1. Furosemide is a diuretic, also known as a water pill, that helps increase urine production and reduce fluid accumulation in the body. It is commonly used to treat edema associated with conditions such as congestive heart failure, liver disease, and kidney disorders.
2. Amiloride is a potassium-sparing diuretic that helps reduce the amount of potassium lost in the urine. It works by blocking the reabsorption of sodium and reducing the amount of fluid retained in the body. This can help in treating conditions such as edema and hypertension.

Frumil, as a combination medication, provides the benefits of both furosemide and amiloride in a single tablet.

How to use

Here are general guidelines for using Frumil:

1. Take with or without food: Medicine can be taken with or without food. However, if it causes an upset stomach, you may take it with food to minimize gastrointestinal discomfort.
2. Swallow the tablet whole: Take the tablet with a full glass of water. Do not crush, chew, or break the tablet before swallowing, as it is designed to release the medication slowly.
3. Take at the same time each day: Establish a routine by taking Frumil at the same time each day. This can help you remember to take it consistently and maintain a steady level of the medication in your body.
4. Stay hydrated: It is important to maintain proper hydration while taking Amiloride.

Dosage

The following dosage information is a general guideline:

Edema (Fluid retention):

• The usual starting dose for adults is one tablet (containing 40 mg furosemide and 5 mg amiloride) taken once or twice a day.
• Your healthcare provider may adjust the dose based on your response to treatment and individual needs.
• The maximum daily dose is typically two tablets (80 mg furosemide and 10 mg amiloride) per day.

Hypertension (High blood pressure):

• The usual starting dose for adults is one tablet (containing 40 mg furosemide and 5 mg amiloride) taken once daily.

Children: The dosage for children will be determined by the healthcare provider based on factors such as the child's age, weight, and medical condition.

Side effects

Here are some common side effects associated with Frumil:

1. Increased urination: Due to the diuretic effect of furosemide, Frumil may cause an increase in urination frequency. This is a normal response to the medication.
2. Electrolyte imbalance: Furosemide and amiloride can affect the levels of electrolytes in your body, such as potassium, sodium, and magnesium. This can sometimes lead to symptoms like muscle cramps, weakness, irregular heartbeat, or changes in mood. Regular monitoring of electrolyte levels may be necessary.
3. Dizziness or lightheadedness: Amiloride can cause dizziness or lightheadedness, especially when standing up quickly. It is important to rise slowly from a sitting or lying position to minimize this effect.
4. Dry mouth or increased thirst: Medicine can sometimes cause a dry mouth or an increased feeling of thirst. Staying well-hydrated and drinking plenty of fluids can help alleviate these symptoms.
5. Gastrointestinal effects: Furosemide and amiloride may cause gastrointestinal disturbances, such as nausea, vomiting, diarrhea, or stomach pain. Taking Frumil with food or adjusting the dose may help reduce these effects.
6. Skin reactions: In rare cases, Frumil may cause skin reactions such as rash or itching.

Storage

When it comes to storing Frumil, it is important to follow the recommended guidelines to maintain the medication's effectiveness and ensure safety. Here are some general storage instructions:

1. Store at room temperature: Keep medicine at a temperature between 68°F (20°C) and 77°F (25°C).
2. Protect from moisture: Store the medication in its original packaging and keep it tightly closed. Protect it from moisture, as excessive humidity can affect the stability of the tablets.
3. Keep away from light: Store tablets away from direct sunlight or sources of intense light. Exposure to light can degrade the medication.
4. Follow specific instructions: Always follow any specific storage instructions provided by your pharmacist or on the product label. Different brands or formulations of Amiloride may have slight variations in storage requirements.
5. Keep out of reach of children and pets: Store Frumil in a secure location that is out of reach of children and pets to prevent accidental ingestion.
6. Do not use expired medication: Check the expiration date on the packaging and do not use Frumil if it has expired. Expired medications may be less effective or potentially harmful.

Overdose

In case of an overdose of Amiloride, it is important to seek immediate medical attention or contact your local emergency services. Overdosing on Frumil can have serious consequences and should be treated as a medical emergency. Here is some general information regarding overdose:

1. Symptoms: Overdose symptoms may vary depending on the amount of medication taken and individual factors. Symptoms can include severe dehydration, electrolyte imbalances (such as low potassium levels), dizziness, confusion, weakness, rapid heartbeat, fainting, seizures, and in severe cases, coma.
2. Medical assistance: If you suspect an overdose, contact emergency medical services or go to the nearest emergency room immediately.
3. Treatment: Treatment for Frumil overdose will focus on removing the excess medication from the body and managing the symptoms. This may include supportive measures such as intravenous fluids to restore hydration and electrolyte balance, close monitoring of vital signs, and appropriate medical interventions to address any complications that may arise.
4. Do not induce vomiting: Vomiting may not be effective or safe in certain situations and should be guided by medical professionals.

Missed Doses

If you miss a dose of Frumil, it is important to take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

Here are a few additional points to keep in mind regarding missed doses of Frumil:

1. Follow the prescribed schedule: Taking Frumil at the same time each day can help maintain consistent levels of the medication in your body and optimize its effectiveness.
2. Set reminders: If you have trouble remembering to take your medication, consider setting reminders such as alarms or using pill organizers to help you stay on track.
3. Do not double dose: If you forget to take a dose, do not take an extra dose to make up for it. Taking more than the prescribed amount can increase the risk of side effects or complications.

 Frumil (pdf)