Tarceva

Erlotinib works by targeting and inhibiting a specific protein called epidermal growth factor receptor (EGFR). EGFR is found on the surface of cancer cells and plays a role in promoting their growth and division. By blocking EGFR, Tarceva helps slow down or stop the growth of cancer cells.

Medicine is usually taken orally in the form of tablets, and the dosing and duration of treatment depend on the specific type and stage of cancer being treated. It is commonly used in combination with other cancer treatments, such as chemotherapy or radiation therapy.

How to use

Here are some general guidelines on how to use Tarceva:

1. Take Tarceva on an empty stomach: Medicine should be taken at least one hour before or two hours after eating food. Swallow the tablet whole with a full glass of water.
2. Take Tarceva at the same time each day: It is recommended to take Tarceva at the same time every day to maintain a consistent level of the medication in your body. This will help ensure its effectiveness.
3. Avoid grapefruit and grapefruit juice: Grapefruit and grapefruit juice may interact with Erlotinib and affect its absorption in the body. It is advisable to avoid consuming grapefruit products while taking Tarceva.
4. Do not double dose: If you miss a dose, take it as soon as you remember, unless it is close to the time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.
5. Be aware of potential side effects: Tarceva may cause side effects, and they can vary from person to person. Common side effects include skin rash, diarrhea, nausea, fatigue, and loss of appetite.

Dosage

The dosage of Tarceva can vary depending on the specific type of cancer being treated and individual patient factors. The following information provides a general overview.

For Non-Small Cell Lung Cancer (NSCLC):

The typical recommended dosage of Tarceva for NSCLC is 150 mg taken once daily. It is usually taken on an empty stomach, at least one hour before or two hours after eating.

For Pancreatic Cancer:

Erlotinib is used in combination with gemcitabine for the treatment of pancreatic cancer. The usual recommended dosage is 100 mg of Tarceva taken once daily, also on an empty stomach. This combination treatment is usually given for as long as it continues to be effective and is well tolerated.

Dosage adjustments and modifications may be necessary depending on individual factors, such as your overall health, any other medications you are taking, and the presence of certain side effects.

Side effects

Tarceva may cause several side effects, although not everyone experiences them. Common side effects include:

1. Skin rash: A rash is one of the most common side effects of Tarceva. It usually appears as acne-like bumps or a dry, itchy, or irritated rash on the face, chest, back, or other areas of the body.
2. Diarrhea: Tarceva can cause diarrhea, which may range from mild to severe.
3. Nausea and vomiting: Some individuals may experience nausea and vomiting while taking Tarceva.
4. Fatigue: Erlotinib can cause fatigue or a general feeling of tiredness. It is advisable to get enough rest and conserve energy while undergoing treatment.
5. Loss of appetite: Some individuals may experience a decreased appetite or weight loss while taking Tarceva.
6. Other potential side effects: Additional side effects that can occur include dry skin, eye irritation, nail changes, hair thinning or changes, abdominal pain, headache, cough, shortness of breath, and infection.

Storage

Tarceva should be stored properly to maintain its effectiveness. Here are some guidelines for storing:

1. Store at room temperature: Medicine should be stored at room temperature, typically between 20°C and 25°C (68°F and 77°F). Keep it in a cool, dry place away from direct sunlight and sources of heat.
2. Protect from moisture: Tarceva tablets should be kept in their original packaging and protected from moisture. Avoid storing them in the bathroom or any area with high humidity, as it may affect the stability of the medication.
3. Keep out of reach of children and pets: Store Erlotinib in a secure location where children or pets cannot access it. It is important to prevent accidental ingestion or misuse.
4. Do not use expired medication: Check the expiration date on the Tarceva packaging and do not use the medication if it has expired. Expired medication may not be as effective and could potentially be harmful.
5. Dispose of unused medication properly: If you have any leftover or unused tablets, do not flush them down the toilet or throw them in the regular trash. Follow local guidelines for medication disposal or consult your pharmacist for the appropriate method of disposal.

Overdose

If an overdose of Erlotinib is suspected, it is important to seek immediate medical attention or contact a poison control center. An overdose can occur if you accidentally take more Tarceva tablets than prescribed or if there is an interaction with other medications.

Symptoms of Tarceva overdose may include severe diarrhea, skin rash, liver problems, gastrointestinal bleeding, or other severe side effects. However, the specific symptoms and their severity can vary from person to person.

When contacting emergency services or a poison control center, provide them with the necessary information, such as the amount of Tarceva taken, the time of ingestion, and any accompanying symptoms. It is also important to inform them about any other medications or substances that have been taken along with Erlotinib.

Treatment for a Tarceva overdose will depend on the severity of symptoms and may involve supportive care to manage the symptoms and close monitoring of vital signs. In some cases, gastric lavage (stomach pumping) or administration of activated charcoal may be considered to reduce the absorption of the medication.

It is crucial to remember that an overdose of any medication can be dangerous, and prompt medical attention is necessary.

Missed Doses

If you miss a dose of Tarceva, here are some general guidelines to follow:

1. Take the missed dose as soon as you remember: If you realize that you missed a dose of Tarceva, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.
2. Do not take extra doses to compensate: It is important not to take an extra dose of Erlotinib to make up for the missed one. Taking more than the prescribed dose can increase the risk of side effects without providing any additional benefit.
3. Maintain the regular dosing schedule: Try to maintain a consistent schedule for taking Tarceva. Taking it at the same time each day helps ensure a steady level of the medication in your body, which is important for its effectiveness.