Xarelto

Medicine works by inhibiting a specific clotting factor in the blood called Factor Xa. By blocking this factor, Xarelto reduces the formation of blood clots and helps prevent conditions such as deep vein thrombosis (DVT), pulmonary embolism (PE), and stroke in patients at risk.

It is commonly prescribed to individuals who have had hip or knee replacement surgery, as it can help prevent the formation of blood clots in the legs. Xarelto is also used to treat and prevent blood clots in people with atrial fibrillation (an irregular heart rhythm) and to reduce the risk of recurrent blood clots in patients who have already experienced a clotting event.

How to use

Here are some general guidelines for using Xarelto:

1. Timing: Medicine can be taken with or without food. It is usually taken once a day, preferably around the same time each day to help maintain a consistent level of the medication in your system.
2. Swallowing the tablet: Take the prescribed Xarelto tablet whole with a glass of water. Do not crush, chew, or break the tablet before swallowing.
3. Precautions: Rivaroxaban is an anticoagulant, so it can increase the risk of bleeding. Avoid activities that may increase the likelihood of bleeding or injury. Be cautious when using sharp objects and be mindful of the potential for bleeding, especially if you have any medical conditions or are taking other medications that can further increase bleeding risk.

Dosage

Here are some general guidelines for the dosage of Xarelto:

Prevention of Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE):

• After Hip Replacement Surgery: The typical recommended dose is 10 milligrams (mg) taken once daily for 35 days.
• After Knee Replacement Surgery: The usual recommended dose is 10 mg taken once daily for 12 days.

Treatment and Prevention of Blood Clots in Atrial Fibrillation:

• The standard dosage for most patients is 20 mg taken once daily with the evening meal.

Treatment of Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE):

• The initial recommended dose is typically 15 mg taken twice daily with food for the first 21 days.
• After the initial treatment period, the recommended dose is usually 20 mg taken once daily with food.

Side effects

Like any medication, Xarelto can cause side effects. Not everyone experiences these side effects, and their severity may vary from person to person. Here are some possible side effects:

1. Bleeding: Rivaroxaban is an anticoagulant, so it can increase the risk of bleeding. This includes bleeding from cuts, nosebleeds, bleeding gums, or prolonged bleeding after injury. In some cases, bleeding can be severe or even life-threatening. Seek medical attention if you notice unusual or excessive bleeding.
2. Bruising: Medicine can make you more prone to bruising or develop bruises more easily than usual.
3. Hemorrhage: In rare cases, Xarelto may cause internal bleeding, leading to symptoms such as blood in urine or stools, coughing up blood, or vomiting blood. If you experience any signs of internal bleeding, seek immediate medical help.
4. Back pain: Some individuals taking Xarelto may experience back pain.
5. Headache: Drug can occasionally cause headaches.
6. Dizziness: Feeling dizzy or lightheaded is a possible side effect of Xarelto.
7. Itching or rash: In rare cases, Xarelto may cause itching or a skin rash. If you develop a severe rash, hives, or experience difficulty breathing, seek immediate medical attention.

Storage

When it comes to storing Xarelto or any medication, it is important to follow the recommended guidelines to ensure its effectiveness and safety. Here are the general storage instructions:

1. Temperature: Store medicine at room temperature, typically between 20°C to 25°C (68°F to 77°F).
2. Protect from moisture: Keep tablets in its original packaging or container with the lid tightly closed to protect it from moisture. Avoid storing it in the bathroom, where moisture levels are high.
3. Keep away from heat and direct sunlight: Store Rivaroxaban in a cool and dry place, away from direct sunlight, excessive heat, or extreme temperature fluctuations. Do not freeze the medication.
4. Childproof storage: Keep Xarelto out of reach and sight of children and pets to prevent accidental ingestion.

It's important to note that these storage guidelines may vary slightly based on the specific packaging and manufacturer's instructions. Always refer to the package insert or consult your pharmacist for any specific storage requirements or precautions for the particular Xarelto product you have.

By following the proper storage recommendations, you can help maintain the quality and integrity of the medication throughout its shelf life.

Overdose

If you suspect an overdose of Rivaroxaban, it is important to seek immediate medical attention or contact your local poison control center. An overdose of Xarelto can increase the risk of bleeding, which may be severe and require urgent medical intervention. Here are some steps to take in the event of a Xarelto overdose:

1. Call emergency services: If someone is experiencing severe symptoms or is unconscious, call emergency services immediately.
2. Provide necessary information: When seeking medical help, be prepared to provide information about the dosage and quantity of Xarelto that was taken, as well as the time of ingestion.
3. Monitor vital signs: Keep a close eye on the individual's vital signs, such as heart rate and blood pressure. If there are any sudden changes or signs of significant bleeding, it is crucial to inform the medical professionals.

In case of an emergency, please dial your emergency services number without delay.

Missed Doses

If you miss a dose of Xarelto, follow these general guidelines:

1. Take the missed dose as soon as you remember: If you realize that you missed a dose and it is not close to the time for your next scheduled dose, take the missed dose as soon as you remember. Ensure that you take it with a glass of water.
2. Skip the missed dose if it's close to the next scheduled dose: If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.
3. Continue with the regular dosing schedule: It is important to resume taking Xarelto according to the prescribed schedule after a missed dose. Taking the medication consistently at the recommended times helps maintain its effectiveness in preventing blood clots.