Antidepressants Drugs OTC
Aripiprazole
Abilify is prescribed for treatment for adults with depression, manic or mixed episodes associated with bipolar disorde, schizophrenia and irritability associated with autistic disorder.
Clomipramine
Anafranil is indicated for treatment of obsessivecompulsive disorder (OCD). It may also be used for other conditions as determined by your doctor.
Amoxapine
Asendin is a medication is used to manage the thoughts and behaviors experienced by people with depression and promotes emotional and behavioral balance.
Bupropion
Bupron SR is medication is used to treat major depressive disorder and seasonal affective disorder and help people stop smoking.
Citalopram
Celexa is an SSR inhibitor, and is used to treat depression. It helps to keep the right balance of chemicals in the brain which prevents depression.
Duloxetine
Cymbalta (Duloxetine) is a serotonin-norepinephrine reuptake inhibitor is used to treat depression and anxiety.
Trazodone
Desyrel is used for treatment of depression. It may also be used for relief of an anxiety disorder (e.g., sleeplessness, tension), chronic pain.
Phenytoin
Dilantin is indicated for treatment of certain types of seizures. It may also be used for other conditions as determined by your doctor.
Venlafaxine
Effexor is an SNR inhibitor, which is used to treat depression. It works by restoring the balance of certain natural substances in the brain.
Amitriptyline
Elavil is a tricyclic antidepressant. They increase the activity of certain chemicals in the brain, which help improve mood.
Amitriptyline
Endep is a tricyclic antidepressant with sedative properties are indicated for the maintenance treatment of major depression.
Lithium
Eskalith (Lithium) is indicated in the treatment of manic episodes of manic-depressive illness and patients with a history of mania.
Ziprasidone
Geodon (Ziprasidone) is used to treat symptoms of schizophrenia and acute manic or mixed episodes associated with bipolar disorder.
Escitalopram
Lexapro is selective serotonin reuptake inhibitors (SSRIs). Lexapro treats depression and generalized anxiety disorder.
Fluvoxamine
Luvox is used to treat obsessive-compulsive disorder (OSD). It may also be used to treat depression and other conditions as determined by your doctor.
Nortriptyline
Nortriptyline is used for treatment of depression. It may also be used for other conditions as determined by your doctor.
Nortriptyline
Pamelor is indicated for treatment of depression. It may also be used for other conditions as determined by your doctor.
Paroxetine
Paxil is used for treating depression or OCD. It may also be used to treat panic disorder, posttraumatic stress disorder, or social anxiety disorder.
Mirtazapine
Remeron is an atypical antidepressant with noradrenergic and specific serotonergic activity is indicated for the symptomatic relief of depressive illness.
Risperidone
Risperdal is used for treatment of schizophrenia or bipolar mania. It may also be used for other conditions as determined by your doctor.
Quetiapine
Seroquel is a medicine for patients with major depressive disorder, acute depressive episodes in bipolar disorder, acute manic or mixed episodes in bipolar disorder and schizophrenia.
Doxepin
Sinequan is a tricyclic antidepressant is used to treat symptoms of depression, manic-depressive conditions, anxiety associated with alcoholism, psychiatric conditions.
Imipramine
Tofranil is medicine for the treatment of depression in adults and may be useful as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.
Imipramine
Venlor is medicine for the treatment of depression, including depression with associated anxiety and revention of relapse of an episode of depression.
Bupropion
Paxil is used for treating depression or OCD. It may also be used to treat panic disorder, posttraumatic stress disorder, or social anxiety disorder.
Olanzapineopion
Zyprexa is an atypical antipsychotic indicated for the treatment of schizophrenia and manic or mixed episodes associated with bipolar disorder.
Different Types Of Antidepressants
Antidepressants step on neurotransmitters at the section of the synaptic cleft. Neurotransmitter’s release and repute and that’s the way of communicating with each other without issues. Antidepressants are thought to stop repute, step up production and help in preventing the disintegration of neurotransmitters thus stepping their action to classify mood and mitigate depression.
There are 20 various types of antidepressants that work specifically. However they all work the same as in mitigating the depression and uplifting the mood they are prescribed according to the type of depressive disorder, collaborating with other medicines or medical problems and the side-effects. They are divided into 4 types –
- Selective serotonin reuptake inhibitors (SSRIs)
- Atypical antidepressants
- Monoamine oxidase inhibitors (MAOIs)
- Tricyclic antidepressants (TCAs)
Two main types of mood stabilizers are MAO that is Monoamine oxidase inhibitors and dual –action antidepressants.
Monoamine oxidase inhibitors are the earliest used mood stabilizers they work by stopping the action of an enzyme called monoamine oxidase which kills off the norepinephrin. They prevent the damage of this neurotransmitter and therefore they remain in the synaptic space for a long time warding off depression. The drugs used are Nardil (phenelzine) and Parnate (tranylcypromine). The patient should give full history to the doctor before using any of the drugs.
Some food needs to be restricted during the course of MAO. This are:
- Soybeans, fava beans and bean curd
- Smoked, fermented, aged, or pickled fish
- Ginseng, St. John's wort, and medication containing 5-HTP
- Sauerkraut
- Shrimp paste
- All cheeses except cottage cheese and cream cheeses
- Beer and spirits, liqueurs, red wine and non-alcoholic beer
- Other foods such as some white wines and port, caffeine, chocolate, dairy products, nuts, raspberries, and spinach are some of the food that should be consumed in a very small quantity.
Tricyclic antidepressants also known as TCA were first used only for schizophrenia they were the first choice. TCA’s include drugs like Allegron (nortriptyline), Sinequan (doxepin), Tofranil (imipramine) and Endep (amitryptyline) work by stopping the repute of neurotransmitter in the synaptic cleft and therefore helps in uplifting the mood. TCAs are not approved for people with a history of seizures glaucoma, heart disease, hyperthyroidism, or urinary retention while except this they are considered safer than MAO.
Selective Serotonin Reuptake Inhibitors (SSRIs) for ex Prozac (fluoxitine), Zoloft (sertraline), Cipramil (citalopram) and Aropax (paroxetine) act on inhibiting the repute of serotonin and help by lifting the depressed mood. SSRI’s are safer from MAO and TCA but sexual dysfunction have been seen after its disuse.
Dual action antidepressants such as venlafaxine (Efexor) and mirtazapine (Avanza) target more than one neurotransmitter. MAO and tricyclic drugs are also used for depressive disorder and mania.
Treatment regimen
- Low doses should be given that should also be monitored
- The improvements occur gradually with the patient getting more sleep and improvement in appetite.
- SSRI’S are the first line treatment; if they don’t work then go for TCA and then lastly MAO’s.